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Prof. Dr Snyders, Dirk, orcid, researcherid

Institute  Top | Institute | Publications 
    University of Antwerp; Faculteit Farmaceutische, Biomedische en Diergeneeskundige Wetenschappen; Departement Biomedische Wetenschappen (BMW), more
    Function: President

    Direct contact at institute:
    Tel.: +32-(0)3-820 23 35
    Fax: +32-(0)3-820 25 41

Publications (8)  Top | Institute | Publications 
    ( 7 peer reviewed ) split up
  • Peer reviewed article Cuypers, E.; Abdel-Mottaleb, Y.; Kopljar, I.; Rainier, J.; Raes, A.L.; Snyders, D.J.; Tytgat, J. (2008). Gambierol, a toxin produced by the dinoflagellate Gambierdiscus toxicus, is a potent blocker of voltage-gated potassium channels. Toxicon 51(6): 974-983., more
  • Peer reviewed article Kopljar, I.; Labro, A.J.; Cuypers, E.; Johnson, H.W.B.; Rainier, J.D.; Tytgat, J.; Snyders, D.J. (2009). A polyether biotoxin binding site on the lipid-exposed face of the pore domain of Kv channels revealed by the marine toxin gambierol. Proc. Natl. Acad. Sci. U.S.A. 106(24): 9896-9901., more
  • Peer reviewed article Kopljar, I.; Labro, A.J.; Rainier, J.D.; Tytgat, J.; Snyders, D.J. (2012). Voltage sensor trapping in voltage-gated K-channels by the marine neurotoxin Gambierol. Toxicon 60(2): 150-151., more
  • Peer reviewed article Kopljar, I.; Labro, A.J.; de Block, T.; Rainier, J.; Tytgat, J.; Snyders, D.J. (2013). The ladder-shaped polyether toxin gambierol anchors the gating machinery of Kv3.1 channels in the resting state. J. Gen. Physiol. 141(3): 359-369., more
  • Kopljar, I.; Peigneur, S.; Snyders, D.J.; Tytgat, J. (2014). The mechanism of action of microalgal toxins interacting with Nav and Kv channels, in: Rossini, G.P. (Ed.) Toxins and biologically active compounds from microalgae: Volume 2. Biological effects and risk management. pp. 3-34, more
  • Peer reviewed article Kopljar, I.; Grottesi, A.; de Block, T.; Rainier, J.D.; Tytgat, J.; Labro, A.J.; Snyders, D.J. (2016). Voltage-sensor conformation shapes the intra-membrane drug binding site that determines gambierol affinity in Kv channels. Neuropharmacology 107: 160-167., more
  • Peer reviewed article Martínez-Morales, E.; Kopljar, I.; Rainier, J.D.; Tytgat, J.; Snyders, D.J.; Labro, A.J. (2016). Gambierol and n-alkanols inhibit Shaker Kv channel via distinct binding sites outside the K+ pore. Toxicon 120: 57-60., more
  • Peer reviewed article Stas, J.; Kopljar, I.; Labro, A.; Peigneur, S.; Zaharenko, A.J.; Tytgat, J.; Snyders, D.J. (2013). A gating modulator peptide toxin for Shaker-type Kv1 channels derived from the sea anemone Bunodosoma cangicum. Biophys. J. 104(2): 125A-125A, more

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