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Oral delivery of chemotherapeutics in marine larviculture of fish and shrimp phase II: optimization and applications
dbs.cordis.lu/cordis-cgi/srchidadb?action=d&session=60432002-2-28&doc=1&tbl=en_proj&rcn=ep_rcn:29428&caller=en_cordis

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Reference no: AIR21600
Period: September 1993 till August 1995
Status: Completed

Thesaurus terms: Aquaculture; Disease treatment; Fish larvae; Live feed
Taxonomic terms: Artemia Leach, 1819 [WoRMS]; Brachionus Pallas, 1766 [WoRMS]
Geographical term: Belgium [Marine Regions]

Institute  Top 
  • Universiteit Gent; Faculteit Bio-ingenieurswetenschappen; Vakgroep Dierlijk Productie; Laboratorium voor Aquacultuur en Artemia Reference Center (ARC), more

Abstract:
The objectives are to examine further the potential of bio-encapsulation of chemotherapeutics in the live food stuffs Brachionus and Artemia for the prevention and/or treatment of disease in larval stages of selected species of cultured marine fish (seabass, seabream, turbot) and to attempt pre-industrial application of this methodology, with the same and, possibly, some additional species.
Specific objectives are:
- To apply and/or develop new analytical methodologies for the quantification of levels of various bio-encapsulated chemotherapeutics into Brachionus and Artemia.
- To optimize the oral delivery methodology of the most suitable chemotherapeutics to the fish larvae.
- To perform challenge tests with specific highly virulent pathogens and their appropriate susceptible fish larvae in order to determine the efficiency of bio- encapsulated therapeutics for the prevention and/or treatment of the induced diseases.
- To perform pre-industrial, large scale trials in cooperation with hatcheries, after the standardization of a reliable and effective therapeutic treatment under laboratory conditons.
- To organize workshop(s) for the dissemination of the results of the project to the staff of interested hatcheries for possible immediate application.

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