IMIS | Flanders Marine Institute

Flanders Marine Institute

Platform for marine research


Publications | Institutes | Persons | Datasets | Projects | Maps
[ report an error in this record ]basket (0): add | show Printer-friendly version

Medetomidine as a candidate antifoulant: sublethal effects on juvenile turbot (Psetta maxima L.)
Hilvarsson, A.; Halldórsson, H.P.; Granmo, A. (2007). Medetomidine as a candidate antifoulant: sublethal effects on juvenile turbot (Psetta maxima L.). Aquat. Toxicol. 83(3): 238-246.
In: Aquatic Toxicology. Elsevier Science: Tokyo; New York; London; Amsterdam. ISSN 0166-445X, more
Peer reviewed article  

Available in Authors 

    Antifouling; Antifouling substances; Medetomidine; Sublethal effects; Psetta maxima (Linnaeus, 1758) [WoRMS]; Marine

Authors  Top 
  • Hilvarsson, A.
  • Halldórsson, H.P.
  • Granmo, A.

    Medetomidine is proposed as a candidate antifouling compound proven effective against barnacles. It is routinely used as a sedative in veterinary medicine. It is therefore important to also investigate possible adverse effects on non-target organisms. Thus, sublethal effects on two different ages of juvenile turbot (Psetta maxima) exposed to a wide concentration range of medetomidine (0.063-420 nM) were assessed after exposure under semistatic as well as flow-through conditions, for a maximum of 96 h. Effects on respiration frequency and amount of oxygen consumed were assessed, as well as the ability of turbot to adapt to a dark background. A significant decrease was seen both in respiration frequency with a lowest observed effect concentration (LOEC) of 2.1 nM as well as in amount of oxygen consumed (LOEC = 420 nM) and colour adaptation (LOEC = 4.2 nM). Colour adaptation was also evaluated in a short exposure experiment, 1 h, where significant effects were observed (LOEC = 2.1 nM). Reversibility, when fish were incubated in clean seawater following exposure, was seen for all observed effects. Ecological relevance of the observed effects is discussed.

All data in IMIS is subject to the VLIZ privacy policy Top | Authors