Medetomidine as a candidate antifoulant: sublethal effects on juvenile turbot (Psetta maxima L.)
In: Aquatic Toxicology. Elsevier Science: Tokyo; New York; London; Amsterdam. ISSN 0166-445X; e-ISSN 1879-1514, more
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| Keywords |
Agents > Antifouling substances
Antifouling
Drugs > Neurotropic drugs > Psychotropic drugs > Neuroleptics > Analgesics > Medetomidine
Sublethal effects
Psetta maxima (Linnaeus, 1758) [WoRMS]
Marine/Coastal |
| Author keywords |
medetomidine; antifouling; Psetta maxima; sublethal effects |
| Authors | | Top |
- Hilvarsson, A.
- Halldórsson, H.P.
- Granmo, A.
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| Abstract |
Medetomidine is proposed as a candidate antifouling compound proven effective against barnacles. It is routinely used as a sedative in veterinary medicine. It is therefore important to also investigate possible adverse effects on non-target organisms. Thus, sublethal effects on two different ages of juvenile turbot (Psetta maxima) exposed to a wide concentration range of medetomidine (0.063-420 nM) were assessed after exposure under semistatic as well as flow-through conditions, for a maximum of 96 h. Effects on respiration frequency and amount of oxygen consumed were assessed, as well as the ability of turbot to adapt to a dark background. A significant decrease was seen both in respiration frequency with a lowest observed effect concentration (LOEC) of 2.1 nM as well as in amount of oxygen consumed (LOEC = 420 nM) and colour adaptation (LOEC = 4.2 nM). Colour adaptation was also evaluated in a short exposure experiment, 1 h, where significant effects were observed (LOEC = 2.1 nM). Reversibility, when fish were incubated in clean seawater following exposure, was seen for all observed effects. Ecological relevance of the observed effects is discussed. |
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