|Medetomidine as a candidate antifoulant: sublethal effects on juvenile turbot (Psetta maxima L.)|Hilvarsson, A.; Halldórsson, H.P.; Granmo, A. (2007). Medetomidine as a candidate antifoulant: sublethal effects on juvenile turbot (Psetta maxima L.). Aquat. Toxicol. 83(3): 238-246. dx.doi.org/10.1016/j.aquatox.2007.04.008
In: Aquatic Toxicology. Elsevier Science: Tokyo; New York; London; Amsterdam. ISSN 0166-445X, more
Antifouling; Antifouling substances; Medetomidine; Sublethal effects; Psetta maxima (Linnaeus, 1758) [WoRMS]; Marine
|Authors|| || Top |
- Hilvarsson, A.
- Halldórsson, H.P.
- Granmo, A.
Medetomidine is proposed as a candidate antifouling compound proven effective against barnacles. It is routinely used as a sedative in veterinary medicine. It is therefore important to also investigate possible adverse effects on non-target organisms. Thus, sublethal effects on two different ages of juvenile turbot (Psetta maxima) exposed to a wide concentration range of medetomidine (0.063-420 nM) were assessed after exposure under semistatic as well as flow-through conditions, for a maximum of 96 h. Effects on respiration frequency and amount of oxygen consumed were assessed, as well as the ability of turbot to adapt to a dark background. A significant decrease was seen both in respiration frequency with a lowest observed effect concentration (LOEC) of 2.1 nM as well as in amount of oxygen consumed (LOEC = 420 nM) and colour adaptation (LOEC = 4.2 nM). Colour adaptation was also evaluated in a short exposure experiment, 1 h, where significant effects were observed (LOEC = 2.1 nM). Reversibility, when fish were incubated in clean seawater following exposure, was seen for all observed effects. Ecological relevance of the observed effects is discussed.