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Amphidinolides B4 and B5, potent cytotoxic 26-membered macrolides from dinoflagellate Amphidinium species
Tsuda, M.; Kariya, Y.; Iwamoto, R.; Fukushi, E.; Kawabata, J.; Kobayashi, J. (2005). Amphidinolides B4 and B5, potent cytotoxic 26-membered macrolides from dinoflagellate Amphidinium species. Mar. Drugs 3(1): 1-8. https://dx.doi.org/10.3390/md301001
In: Marine Drugs. Molecular Diversity Preservation International (MDPI): Basel. ISSN 1660-3397; e-ISSN 1660-3397, more
Peer reviewed article  

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Keywords
    Properties > Biological properties > Toxicity > Cytotoxicity
    Amphidinium Claperède & Lachmann, 1859 [WoRMS]; Dinophyceae [WoRMS]
    Marine/Coastal

Authors  Top 
  • Tsuda, M.
  • Kariya, Y.
  • Iwamoto, R.
  • Fukushi, E.
  • Kawabata, J.
  • Kobayashi, J.

Abstract
    Two new cytotoxic 26-membered macrolides, amphidinolides B4 (1) and B5 (2), have been isolated from a marine dinoflagellate Amphidinium sp. (strain Y-100), and the structures were elucidated on the basis of detailed analyses of 2D NMR data including 13C-13C correlations.

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