IMIS

Publications | Institutes | Persons | Datasets | Projects | Maps
[ report an error in this record ]basket (0): add | show Print this page

A functional approach to transcriptome profiling: linking gene expression patterns to metabolites that matter
Hoover, C.A.; Slattery, M.; Marsh, A.G. (2007). A functional approach to transcriptome profiling: linking gene expression patterns to metabolites that matter. Mar. Biotechnol. 9(4): 411-419. https://dx.doi.org/10.1007/s10126-007-9008-2
In: Marine Biotechnology. Springer-Verlag: New York. ISSN 1436-2228; e-ISSN 1436-2236, more
Peer reviewed article  

Available in  Authors 

Keywords
    Disciplines > Biology > Molecular biology > Genetics > Genomics
    Gene expression
    Genomes
    Metabolites > Secondary metabolites
    Transcriptome
    Marine/Coastal
Author keywords
    gene expression; genomics; secondary metabolite; transcriptome

Authors  Top 
  • Hoover, C.A.
  • Slattery, M.
  • Marsh, A.G.

Abstract
    Secondary metabolites or natural products have been isolated from many marine organisms. These metabolites often have important bioactive functions; however, very little information is available regarding the biosynthesis and regulation of many secondary metabolites. At a time when use of marine-derived metabolites is rapidly expanding in industry and pharmacological fields, a better understanding of the genetic mechanisms controlling secondary metabolite production is necessary. We review the recent development of a novel transcriptome profiling methodology that allows for rapid and high-throughput screening of changes in mRNA sequence pools. The application of genomics-based techniques and the integration of both biochemical and molecular data sets in marine organisms complement ongoing drug discovery efforts.

All data in the Integrated Marine Information System (IMIS) is subject to the VLIZ privacy policy Top | Authors