The quantitative cytochemical effects of three metal ions on a lysosomal hydrolase of a hydroid
Moore, M.N.; Stebbing, A.R.D. (1976). The quantitative cytochemical effects of three metal ions on a lysosomal hydrolase of a hydroid. J. Mar. Biol. Ass. U.K. 81(2): 995-1005
In: Journal of the Marine Biological Association of the United Kingdom. Cambridge University Press/Marine Biological Association of the United Kingdom: Cambridge. ISSN 0025-3154; e-ISSN 1469-7769, more
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| Keywords |
Chemical elements > Metals > Heavy metals
Chemical elements > Metals > Heavy metals > Cadmium
Chemical elements > Metals > Heavy metals > Mercury
Chemical elements > Metals > Transition elements > Heavy metals > Copper
Enzymes
Membranes > Cell constituents > Cell membranes
Pollution effects
Population functions > Growth
Properties > Biological properties > Toxicity
Campanularia flexuosa (Alder, 1857) [WoRMS]
Marine/Coastal |
| Authors | | Top |
- Moore, M.N.
- Stebbing, A.R.D.
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| Abstract |
The quantitative effects of Cu2+, Cd2+, and Hg2+ on the cytochemical staining reaction for lysosomal N-acety1-{beta}-D- glucosaminidase have been determined and related to the inhibitory effects of the metals on colonial growth rate in the experimentally cultured hydroid Campanularia flexuosa. Cytochemical threshold concns are comparable to known environmental levels and are about 1 order of magnitude lower than those obtained by measuring colony growth rates. Pretreatment of colonies with Cu2+ gave no indication of tolerance adaptation, although there is evidence of the cumulative toxicity of Cu2+ and the possible sequestration of this metal in endodermal cell lysosomes. There is also an indication that the Cu2+ may exert its toxic effect by decreasing the stability of the lysosomal membranes, thus increasing the level of free glucosaminidase activity. |
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