Flanders Marine Institute

Platform for marine research

In:

IMIS

Publications | Institutes | Persons | Datasets | Projects | Maps
report an error in this recordbasket (0): add | show Printer-friendly version

Neurotoxic shellfish poisoning
Watkins, S.M.; Reich, A.; Fleming, L.E; Hammond, R.D. (2008). Neurotoxic shellfish poisoning. Mar. Drugs 6(3): 431-455. dx.doi.org/10.3390/md6030431
In: Marine Drugs. Molecular Diversity Preservation International (MDPI): Basel. ISSN 1660-3397, more
Peer reviewed article

Available in Authors 

Keywords
    Algal blooms; Epidemiology; Human health; Red tides; Shellfish poisoning (catching method); Dinoflagellida [WoRMS]; Dinophyceae [WoRMS]; Karenia brevis (C.C.Davis) G.Hansen & Ø.Moestrup, 2000 [WoRMS]; Marine

Authors  Top 
  • Watkins, S.M.
  • Reich, A.
  • Fleming, L.E
  • Hammond, R.D.

Abstract
    Neurotoxic shellfish poisoning (NSP) is caused by consumption of molluscan shellfish contaminated with brevetoxins primarily produced by the dinoflagellate, Karenia brevis. Blooms of K. brevis, called Florida red tide, occur frequently along the Gulf of Mexico. Many shellfish beds in the US (and other nations) are routinely monitored for presence of K. brevis and other brevetoxin-producing organisms. As a result, few NSP cases are reported annually from the US. However, infrequent larger outbreaks do occur. Cases are usually associated with recreationally-harvested shellfish collected during or post red tide blooms. Brevetoxins are neurotoxins which activate voltage-sensitive sodium channels causing sodium influx and nerve membrane depolarization. No fatalities have been reported, but hospitalizations occur. NSP involves a cluster of gastrointestinal and neurological symptoms: nausea and vomiting, paresthesias of the mouth, lips and tongue as well as distal paresthesias, ataxia, slurred speech and dizziness. Neurological symptoms can progress to partial paralysis; respiratory distress has been recorded. Recent research has implicated new species of harmful algal bloom organisms which produce brevetoxins, identified additional marine species which accumulate brevetoxins, and has provided additional information on the toxicity and analysis of brevetoxins. A review of the known epidemiology and recommendations for improved NSP prevention are presented.

 Top | Authors