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Endocrine pancreas morphogenesis of Bufo Bufo during metamorphosis
Grassi Milano, E.; Accordi, F.; Chimenti, C. (1995). Endocrine pancreas morphogenesis of Bufo Bufo during metamorphosis. Neth. J. Zool. 45(1-2): 216-218
In: Netherlands Journal of Zoology. E.J. Brill: Leiden. ISSN 0028-2960, more
Peer reviewed article  

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    Marine; Terrestrial

Authors  Top 
  • Grassi Milano, E.
  • Accordi, F.
  • Chimenti, C.

    Anatomical modifications, immunohistochemisty and cytology of the pancreas during metamorphosis of Bufo Bufo were studied. Endocrine insulin-producing cells appear at the beginning of metamorphosis, cells producing glucagon, somatostatin (14) and pancreatic polypeptide (PP) appear together, a few days later. Extensive anatomical remoddeling, determined by programmed cell death and mitosis occured during metamorphic climax and later, until the adult structure is attained

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