one publication added to basket [2185] | Direct mass spectrometry of buccal ganglia and nerves reveals the processing and targeting of peptide messenger involved in feeding behaviour of Lymnaea
Li, K.W.; Van Minnen, J.; Van Der Greef, J.; Geraerts, W.P.M. (1994). Direct mass spectrometry of buccal ganglia and nerves reveals the processing and targeting of peptide messenger involved in feeding behaviour of Lymnaea. Neth. J. Zool. 44(3-4): 432-438
In: Netherlands Journal of Zoology. E.J. Brill: Leiden. ISSN 0028-2960; e-ISSN 1568-542X, more
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Authors | | Top |
- Li, K.W.
- Van Minnen, J.
- Van Der Greef, J.
- Geraerts, W.P.M.
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Abstract |
Feeding in molluscs is initiated and modulated by central neurons, especially those located in the buccal ganglia. Many of these neurons use diverse peptides as neuromessengers. Direct matrix-assisted laser desorption mass spectrometric analyses of tissues demonstrates that a large number of peptides are present in the buccal ganglia. Furthermore, the newly identified -LFRFamide peptides are shown to target to both the buccal mass and the oesophagus. In accordance to the mass spectrometric data, immunocytochemistry using antibodies against Lymnaea inhibitory peptide indicates that the nerves that innervate the oesophagus are indeed heavily immunoreactive, and the nerves that innervate the buccal mass are only faintly immunoreactive. |
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