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A PCR survey of Hox genes in the myzostomid Myzostoma cirriferum
Bleidorn, C.; Lanterbecq, D.; Eeckhaut, I.; Tiedemann, R. (2009). A PCR survey of Hox genes in the myzostomid Myzostoma cirriferum. Dev. Genes Evol. 219(4): 211-216.
In: Development, Genes and Evolution. Springer: Berlin; Heidelberg. ISSN 0949-944X, more
Peer reviewed article  

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Author keywords
    Myzostomida; Annelida; Hox genes; Platyhelminthes; Phylogeny

Authors  Top 
  • Bleidorn, C.
  • Lanterbecq, D., more
  • Eeckhaut, I., more
  • Tiedemann, R.

    Using degenerate primers, we were able to identify seven Hox genes for the myzostomid Myzostoma cirriferum. The recovered fragments belong to anterior class (Mci_lab, Mci_pb), central class (Mci_Dfd, Mci_Lox5, Mci_Antp, Mci_Lox4), and posterior class (Mci_Post2) paralog groups. Orthology assignment was verified by phylogenetic analyses and presence of diagnostic regions in the homeodomain as well as flanking regions. The presence of Lox5, Lox4, and Post2 supports the inclusion of Myzostomida within Lophotrochozoa. We found signature residues within flanking regions of Lox5, which are also found in annelids, but not in Platyhelminthes. As such the available Hox genes data of myzostomids support an annelid relationship.

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