|Epithelial immunity in a marine invertebrate: a cytolytic activity from a cuticular secretion of the American horseshoe crab, Limulus polyphemus|Harrington, J.M.; Leippe, M.; Armstrong, P.B. (2008). Epithelial immunity in a marine invertebrate: a cytolytic activity from a cuticular secretion of the American horseshoe crab, Limulus polyphemus. Mar. Biol. (Berl.) 153(6): 1165-1171. hdl.handle.net/10.1007/s00227-007-0888-5
In: Marine Biology. Springer: Heidelberg; Berlin. ISSN 0025-3162, more
|Authors|| || Top |
- Harrington, J.M.
- Leippe, M.
- Armstrong, P.B.
The cuticle of the American horseshoe crab, Limulus polyphemus, is largely free of the macroscopic epibionts that rapidly colonize most solid surfaces exposed to sea water. Here, we describe a viscous surface secretion that coats the carapace of the horseshoe crab. We report methods for stimulating production of the substance, identify hemolytic and liposome-permeabilizing activities and provide a partial biochemical characterization. We propose that this secretion functions as an anti-fouling agent protecting the chitinized epithelium of the cuticle from colonization by deleterious epibionts.