(2R,3R,7Z)-2-aminotetradec-7-ene-1,3-diol, a new amino alcohol from the Caribbean sponge Haliclona vansoesti
Devijver, C.; Salmoun, N.; Daloze, D.; Braekman, J.C.; De Weerdt, W.H.; De Kluijver, M.J.; Gomez, R. (2000). (2R,3R,7Z)-2-aminotetradec-7-ene-1,3-diol, a new amino alcohol from the Caribbean sponge Haliclona vansoesti. J. Nat. Prod. 63(7): 978-980. https://dx.doi.org/10.1021/np000081c
In: Journal of Natural Products. American Chemical Society/American Society of Pharmacognosy: Washington DC. ISSN 0163-3864; e-ISSN 1520-6025, more
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| Authors | | Top |
- Devijver, C.
- Salmoun, N.
- Daloze, D.
- Braekman, J.C.
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- De Weerdt, W.H.
- De Kluijver, M.J.
- Gomez, R.
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| Abstract |
The Caribbean marine sponge Haliclona vansoesti was found to contain a high amount (5% dry wt) of a new analogue of 4-sphingenine, (2R,3R,7Z)-2-aminotetradec-7-ene-1,3-diol (1). Its structure was determined by detailed spectroscopic analysis. The relative configuration was deduced from the NMR data of the corresponding acetonide 5, while the absolute configuration was secured via protection of the primary alcohol and amino groups, and esterification of the secondary alcohol with Mosher's reagent. |
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