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Diterpenes with unprecedented skeletons from the red alga Sphaerococcus coronopifolius
Smyrniotopoulos, V.; Kiss, R.; Mathieu, V.; Vagias, C.; Roussis, V. (2015). Diterpenes with unprecedented skeletons from the red alga Sphaerococcus coronopifolius. European Journal of Organic Chemistry 2015(13): 2848-2853. dx.doi.org/10.1002/ejoc.201500133
In: European Journal of Organic Chemistry. WILEY-V C H VERLAG GMBH: Weinheim. ISSN 1434-193X, more

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Keyword
    Marine
Author keywords
    Natural products; Terpenoids; Diterpenes; Structure elucidation

Authors  Top 
  • Smyrniotopoulos, V.
  • Kiss, R.
  • Mathieu, V.
  • Vagias, C.
  • Roussis, V.

Abstract
    Three previously unknown diterpenes – spirosphaerol (1), anthrasphaerol (2) and corfusphaeroxide (3) – have been isolated from the red alga Sphaerococcus coronopifolius. Their structures were elucidated by spectral analysis, including NMR and MS. The isolated metabolites were evaluated for their in vitro antitumour activities against one murine and five human cancer cell lines.

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