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A challenging insight on the structural unit 1 of molluscan Rapana venosa hemocyanin
Dolashka-Angelova, P.; Stevanovic, S.; Dolashki, A.; Devreese, B.; Tzvetkova, B.; Voelter, W.; Van Beeumen, J.; Salvato, B. (2007). A challenging insight on the structural unit 1 of molluscan Rapana venosa hemocyanin. Arch. Biochem. Biophys. 459(1): 50-58. dx.doi.org/10.1016/j.abb.2006.12.009
In: Archives of biochemistry and biophysics. ELSEVIER SCIENCE INC: San Diego, CA,. ISSN 0003-9861, more
Peer reviewed article  

Available in Authors 

Author keywords
    glycoprotein; hemocyanin; Rapana venosa; quaternary structure

Authors  Top 
  • Dolashka-Angelova, P.
  • Stevanovic, S.
  • Dolashki, A.
  • Devreese, B.
  • Tzvetkova, B.
  • Voelter, W.
  • Van Beeumen, J.
  • Salvato, B.

Abstract
    Hemocyanins of mollusks are high molecular mass glycoproteins with a complex quaternary structure which still remains to be defined in detail for most of its species as far as number, spatial distribution and interactions of their structural units is concerned. In the present study, we isolated the functional units of the structural subunit RvH1 of Rapana venosa hemocyanin, combining enzymatic and non-enzymatic methods. Our results suggest that Hc's carbohydrate moieties play a basic role in the organization of the structural units, resulting from post-translational polymerization of the 50 kDa functional units and involving sugar moieties that link between them.

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