|5-Hydroxytryptamine-derived alkaloids from two marine sponges of the genus Hyrtios|Salmoun, M.; Devijver, C.; Daloze, D.; Braekman, J.C.; Van Soest, R.W.M. (2002). 5-Hydroxytryptamine-derived alkaloids from two marine sponges of the genus Hyrtios. J. Nat. Prod. 65(8): 1173-1176. dx.doi.org/10.1021/np020009+
In: Journal of Natural Products. American Chemical Society/American Society of Pharmacognosy: Washington, DC, etc.. ISSN 0163-3864, more
|Authors|| || Top |
- Salmoun, M.
- Devijver, C.
- Daloze, D.
- Braekman, J.C., more
- Van Soest, R.W.M., more
Indonesian specimens of the marine sponges Hyrtios erectus and H. reticulatus were found to contain 5-hydroxytryptamine-derived alkaloids. Their structures were determined on the basis of their spectral properties. H. erectus contained hyrtiosulawesine (4), a new β-carboline alkaloid, together with the already known alkaloids 5-hydroxyindole-3-carbaldehyde (1), hyrtiosin B (2), and 5-hydroxy-3-(2-hydroxyethyl)indole (3). H. reticulatus contained the novel derivative 1,6-dihydroxy-1,2,3,4-tetrahydro-β-carboline (11) together with serotonin (5), 6-hydroxy-1-methyl-1,2,3,4-tetrahydro-β-carboline (7), and 6-hydroxy-3,4-dihydro-1-oxo-β-carboline (9).