IMIS | Flanders Marine Institute

Flanders Marine Institute

Platform for marine research


Publications | Institutes | Persons | Datasets | Projects | Maps
[ report an error in this record ]basket (0): add | show Print this page

Migratory appendicular muscles precursor cells in the common ancestor to all vertebrates
Okamoto, E.; Kusakabe, R.; Kuraku, S.; Hyodo, S.; Robert-Moreno, A.; Onimaru, K.; Sharpe, J.; Kuratani, S.; Tanaka, M. (2017). Migratory appendicular muscles precursor cells in the common ancestor to all vertebrates. Nature Ecology & Evolution 1(11): 1731-1736.
In: Nature Ecology & Evolution. Springer Nature. ISSN 2397-334X, more
Peer reviewed article  

Available in  Authors 

Authors  Top 
  • Okamoto, E.
  • Kusakabe, R.
  • Kuraku, S.
  • Hyodo, S.
  • Robert-Moreno, A.
  • Onimaru, K.
  • Sharpe, J.
  • Kuratani, S.
  • Tanaka, M.

    In amniote embryos, skeletal muscles in the trunk are derived from epithelial dermomyotomes, the ventral margin of which extends ventrally to form body wall muscles. At limb levels, ventral dermomyotomes also generate limb-muscle precursors, an Lbx1-positive cell population that originates from the dermomyotome and migrates distally into the limb bud. In elasmobranchs, however, muscles in the paired fins were believed to be formed by direct somitic extension, a developmental pattern used by the amniote body wall muscles. Here we re-examined the development of pectoral fin muscles in catsharks, Scyliorhinus, and found that chondrichthyan fin muscles are indeed formed from Lbx-positive muscle precursors. Furthermore, these precursors originate from the ventral edge of the dermomyotome, the rest of which extends towards the ventral midline to form body wall muscles. Therefore, the Lbx1-positive, de-epithelialized appendicular muscle precursors appear to have been established in the body plan before the divergence of Chondrichthyes and Osteichthyes.

All data in the Integrated Marine Information System (IMIS) is subject to the VLIZ privacy policy Top | Authors