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Histopathological, serum enzyme, cholesterol and urea changes in experimental acute toxicity of ammonia in common carp Cyprinus carpio and use of natural zeolite for prevention
Peyghan, R.; Takamy, G.A. (2002). Histopathological, serum enzyme, cholesterol and urea changes in experimental acute toxicity of ammonia in common carp Cyprinus carpio and use of natural zeolite for prevention. Aquacult. Int. 10(4): 317-325
In: Aquaculture International. Springer: London. ISSN 0967-6120, more
Peer reviewed article  

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Keywords
    Alkaline earth metals; Ammonia; Common carp; Histopathology; Toxicity; Urea; Zeolites; Cyprinus carpio Linnaeus, 1758 [WoRMS]

Authors  Top 
  • Peyghan, R., correspondent
  • Takamy, G.A.

Abstract
    Common carp, Cyprinus carpio, was exposed to ammonia in a series of acute toxicity tests at 20-22 °C. 24 -h LC50 values were estimated 123 mg/l total ammonia-N (45.5 mg/l molecular ammonia-N). In the lethal concentration of ammonia for common carp (150 mg/l total ammonia), the application of 10 g/l natural zeolite prevented the fish mortalities. In histopathologic study, the most important lesions that encountered in the gill were hyperemia, edema and aneurysm. In the kidney, degenerative changes of tubules and glumeruli, expansion of Bowman's capsules, hyperemia, congestion and hemorrhage were the most prominent lesions. There were hyperemia, degeneration and the presence of some necrotic aria as the only lesions observed in the liver. In the serum the level of alkaline phosphatase (ALP) and urea of experimental groups were significantly higher than the control. There was no significant difference in other enzymes and cholesterol level between experimental groups and control fishes.

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