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Concepts in imaging and microscopy: imaging membrane potential with voltage-sensitive dyes
Zochowski, M.; Wachowiak, M.; Falk, C.X.; Cohen, L.B.; Lam, Y.W.; Antic, S.; Zecevic, D. (2000). Concepts in imaging and microscopy: imaging membrane potential with voltage-sensitive dyes. Biol. Bull. 198: 1-21
In: Biological Bulletin. Marine Biological Laboratory: Lancaster, Pa. etc.. ISSN 0006-3185, more
Peer reviewed article  

Available in Authors 

Keyword
    Marine

Authors  Top 
  • Zochowski, M.
  • Wachowiak, M.
  • Falk, C.X.
  • Cohen, L.B.
  • Lam, Y.W.
  • Antic, S.
  • Zecevic, D.

Abstract
    Membrane potential can be measured optically using a variety of molecular probes. These measurements can be useful in studying function at the level of an individual cell, for determining how groups of neurons generate a behavior, and for studying the correlated behavior of populations of neurons. Examples of the three kinds of measurements are presented. The signals obtained from these measurements are generally small. Methodological considerations necessary to optimize the resulting signal-to-noise ratio are discussed.

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