Angiotensin I-converting enzyme-like activity in a cephalochordate
In: Journal of the Marine Biological Association of the United Kingdom. Cambridge University Press/Marine Biological Association of the United Kingdom: Cambridge. ISSN 0025-3154; e-ISSN 1469-7769, more
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Authors | | Top |
- Cobb, C.S.
- Rundle, J.
- Frankling, S.C.
- Brown, J.A.
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Abstract |
The presence of angiotensin I-converting enzyme-like activity (ACELA) was investigated in whole body homogenates of Branchiostoma lanceolatum using a highly sensitive fluorimetric assay. The measured enzyme activity was inhibited by the two angiotensin converting enzyme inhibitors, captopril and enalapril, suggesting a biochemical pathway that could generate the angiotensins observed in the central nervous system of amphioxus. |
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