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Angiotensin I-converting enzyme-like activity in a cephalochordate
Cobb, C.S.; Rundle, J.; Frankling, S.C.; Brown, J.A. (2003). Angiotensin I-converting enzyme-like activity in a cephalochordate. J. Mar. Biol. Ass. U.K. 83(6): 1307-1308
In: Journal of the Marine Biological Association of the United Kingdom. Cambridge University Press/Marine Biological Association of the United Kingdom: Cambridge. ISSN 0025-3154, more
Peer reviewed article  

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  • Cobb, C.S.
  • Rundle, J.
  • Frankling, S.C.
  • Brown, J.A.

Abstract
    The presence of angiotensin I-converting enzyme-like activity (ACELA) was investigated in whole body homogenates of Branchiostoma lanceolatum using a highly sensitive fluorimetric assay. The measured enzyme activity was inhibited by the two angiotensin converting enzyme inhibitors, captopril and enalapril, suggesting a biochemical pathway that could generate the angiotensins observed in the central nervous system of amphioxus.

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