IMIS | Flanders Marine Institute
 

Flanders Marine Institute

Platform for marine research

IMIS

Publications | Institutes | Persons | Datasets | Projects | Maps
[ report an error in this record ]basket (0): add | show Printer-friendly version

A comparative assessment of the adrenotoxic effects of cadmium in two teleost species, rainbow trout, Oncorhynchus mykiss, and yellow perch, Perca flavescens
Lacroix, A.; Hontela, A. (2004). A comparative assessment of the adrenotoxic effects of cadmium in two teleost species, rainbow trout, Oncorhynchus mykiss, and yellow perch, Perca flavescens. Aquat. Toxicol. 67(1): 13-21. dx.doi.org/10.1016/j.aquatox.2003.11.010
In: Aquatic Toxicology. Elsevier Science: Tokyo; New York; London; Amsterdam. ISSN 0166-445X, more
Peer reviewed article  

Available in Authors 

Keywords
    Cortisol; Endocrinology; Fish; In vitro; Metals; Oncorhynchus mykiss (Walbaum, 1792) [WoRMS]; Perca flavescens (Mitchill, 1814) [WoRMS]; Marine; Brackish water; Fresh water

Authors  Top 
  • Lacroix, A.
  • Hontela, A., correspondent

Abstract
    Rainbow trout (Oncorhynchus mykiss) and yellow perch (Perca flavescens) have a different sensitivity to cadmium (Cd) in vivo (troutO.mykiss = 175.6>LC50/EC50P.flavescens = 37.7). Adrenocortical cells of trout were more sensitive than those of perch and Cd had a higher endocrine-disrupting potential and specificity in trout than in perch. However, in both species, Cd had the same effect on ACTH, dbcAMP and pregnenolone-stimulated cortisol secretion, with pregnenolone maintaining cortisol secretion until cell viability was impaired. These results confirm that for both species, Cd interferes in the signalling pathway of cortisol synthesis in a step prior to the pregnenolone formation. Data provided by the present study revealed important differences in vulnerability of adrenal steroidogenesis between rainbow trout and yellow perch.

All data in IMIS is subject to the VLIZ privacy policy Top | Authors