|The nervous system of Loligo pealei provides multiple models for analysis of organelle motility|
Leopold, P.L.; Lin, J.-W.; Sugimori, M.; Llinás, R.; Brady, S.T. (1995). The nervous system of Loligo pealei provides multiple models for analysis of organelle motility, in: Abbott, N.J. et al. (Ed.) Cephalopod neurobiology: neuroscience studies in squid, octopus and cuttlefish. pp. 15-34
In: Abbott, N.J.; Williamson, R.; Maddock, L. (Ed.) (1995). Cephalopod neurobiology: neuroscience studies in squid, octopus and cuttlefish. Oxford University Press: London. ISBN 0-19-854790-0. 542 pp., more
|Authors|| || Top |
- Leopold, P.L.
- Lin, J.-W.
- Sugimori, M.
The squid, Loligo, has come to be synonymous with the study of electrophysiology. However, L. pealei has also made significant contributions in a number of other fields of neurobiology including intracellular transport and targeting. This chapter discusses the use of the squid giant axon and giant synapse in the study of organelle motility. Special attention is paid to the construction of the model systems, and each preparation is illustrated with an example of the model's utility in research on translocating organelles. The giant axon and the giant synapse have taught us principles regarding the enzymology, pharmacology and biochemistry of organelle transport and are likely to increase our understanding of motility mechanisms in the future.