IMIS | Flanders Marine Institute
 

Flanders Marine Institute

Platform for marine research

IMIS

Publications | Institutes | Persons | Datasets | Projects | Maps
[ report an error in this record ]basket (0): add | show Printer-friendly version

Cyclic nucleotide homeostasis and axonal G proteins in the squid Loligo forbesi
Allen, T.J.A.; Rouot, B. (1995). Cyclic nucleotide homeostasis and axonal G proteins in the squid Loligo forbesi, in: Abbott, N.J. et al. (Ed.) Cephalopod neurobiology: neuroscience studies in squid, octopus and cuttlefish. pp. 35-52
In: Abbott, N.J.; Williamson, R.; Maddock, L. (Ed.) (1995). Cephalopod neurobiology: neuroscience studies in squid, octopus and cuttlefish. Oxford University Press: London. ISBN 0-19-854790-0. 542 pp., more

Available in  Authors 
    VLIZ: Mollusca [8328]

Keyword
    Marine

Authors  Top 
  • Allen, T.J.A.
  • Rouot, B.

Abstract
    This chapter reviews studies on signal: transduction coupling in the squid giant axon and its associated Schwann cell sheath, and the role of cyclic nucleotides and G-proteins in this coupling. The cAMP content of the axon is increased by external application of serotonin (5HT), and this effect is modulated by [Ca²+]i and is dependent on internal GTP; membrane G-proteins are implicated in the coupling. Lowering [Mg²+]i attenuates 5HT -evoked adenylate cyclase activity. The giant axon provides too little G-protein for analysis, but it has been possible to demonstrate G-proteins in the richer source of squid optic lobes. The cGMP content of the axon is increased by carbachol, and by nitroprusside, an agent activating cGMP synthesis. The role of G-proteins in Schwann cell-axon signalling is discussed.

All data in IMIS is subject to the VLIZ privacy policy Top | Authors