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Open Marine Archive |
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| Live-food mediated drug delivery as a tool for disease treatment in larviculture: 2. A case study with European seabass |
| Chair, M.; Romdhane, M.S.; Dehasque, M.; Nelis, H.; De Leenheer, A.P.; Sorgeloos, P. (1991). Live-food mediated drug delivery as a tool for disease treatment in larviculture: 2. A case study with European seabass Spec. Publ. Eur. Aquacult. Soc. 15: 412-414 |
| In: Special Publication European Aquaculture Society. European Aquaculture Society: Bredene. ISSN 0774-0689, meer |
| Ook gepubliceerd als |
- Chair, M.; Romdhane, M.S.; Dehasque, M.; Nelis, H.; De Leenheer, A.P.; Sorgeloos, P. (1991). Live-food mediated drug delivery as a tool for disease treatment in larviculture: 2. A case study with European seabass, in: (1991). IZWO Coll. Rep. 21(1991). IZWO Collected Reprints, 21: pp. chapter 6 [Subsequent publication], meer
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| Trefwoorden |
Antibiotics; Aquaculture techniques; Disease control; Fish culture; Food additives; Vislarven; Voedingsorganismen; Dicentrarchus labrax [Zeebaars] [WoRMS]; Marien |
| Abstract |
The purpose of this study is to investigate the possibility of oral delivery of the antibiotics Trimethoprim (TMP) and Sulfamethoxazole (SMX) to marine fish larvae through incorporation of these antibiotics into the live food organism Artemia. SMX and TMP were selected for their wide range action against gram negative pathogenic bacteria and because of their limited solubility in seawater. Ormetoprim-Sulfadimethoxine (brand name Romet-30) is a new combination of a similar antimicrobial drug used in aquaculture. Diseased penaeid larvae fed Romet-30 through the food chain exhibited greater survival than the untreated ones. In an earlier study Verpraet have described a technique for bioencapsulating high doses of more than 500 mu g TMP + SMX per gram dry weight (DW) Artemia nauplii. In this study we have used 2-month-old European seabass (Dicentrarchus labrax) larvae that were fed with TMP + SMX - bioencapsulated Artemia nauplii. |
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