Open Marien Archief | Vlaams Instituut voor de Zee

Vlaams Instituut voor de Zee

Platform voor marien onderzoek

In:

Open Marien Archief

Het Open Marien Archief van België (OMA) biedt vrije toegang tot de digitale publicaties over de Vlaamse kust en het Belgisch deel van de Noordzee, en alle andere mariene, estuariene en kustgebonden publicaties van Belgische auteurs en wetenschappers en van buitenlandse wetenschappers geaffilieerd aan een Belgische instelling.

Meer info

Nieuwe zoekopdracht
[ meld een fout in dit record ]mandje (1): toevoegen | toon Print-vriendelijke versie

one publication added to basket [102590]
Distribution and ecotoxicity of chlorotriazines in the Scheldt estuary (Belgium-Netherlands)
Noppe, H.; Ghekiere, A.; Verslycke, T.; De Wulf, E.; Verheyden, K.; Monteyne, E.; Polfliet, K.; Van Caeter, P.; Janssen, C.R.; De Brabander, H.F. (2006). Distribution and ecotoxicity of chlorotriazines in the Scheldt estuary (Belgium-Netherlands), in: Noppe, H. (2006). Analytiek van hormoon verstorende stoffen in milieumatrices = Analytics of endocrine disrupting chemicals in environmental matrices. pp. 85-105
In: Noppe, H. (2006). Analytiek van hormoon verstorende stoffen in milieumatrices = Analytics of endocrine disrupting chemicals in environmental matrices. PhD Thesis. Universiteit Gent. Faculteit Diergeneeskunde: Gent. ISBN 978-90-5864-100-7. 153 pp., meer

Beschikbaar in Auteurs 

Trefwoorden

Project Top | Auteurs 
  • Endocrine disruption in the Scheldt Estuary: distribution, exposure and effects, meer

Auteurs  Top 
  • Monteyne, E., meer
  • Polfliet, K.
  • Van Caeter, P., meer
  • Janssen, C.R., meer
  • De Brabander, H.F., meer

Abstract
    The continuous introduction of new products used as growth promoters in animal husbandry, for sports doping and as products for body-building requires residue laboratories to initiate research on developing a strategy for the identification of ’unknown’ components. In this study, a strategy is presented for elucidating the identity, the structure and the possible effects of illegal estrogenic compounds in an unidentified water-based solution. To obtain complete information on the composition and activity of the unidentified product, a multidisciplinary approach was needed. A case-study is described with a ’solution X’ found during a raid. First, in vivo techniques (animal trials with mice, anatomical and histological research) were combined with in vitro techniques (the yeast estrogenic screen (YES)). In a later stage of the investigation, HPLC-fractionation, liquid chromatography–multiple mass spectrometry (LC-MS n and gas chromatography-multiple mass spectrometry (GC-MS n were used. Finally, the identity of ’solution X’ was confirmed in a very low concentration range (10 ng/L estrone and 400 ng/l ethinyloestradiol).

 Top | Auteurs