ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Bisphenol A
Study details
Groupmammalian
OrganismAlpk:AP rat, female
Tissue
Age21-22 days
InVivoIn vivo
LabLaboratory
Flow
Duration3 days
RouteSubcutaneous
Temperature
Concentration400-800 mg/kg/day
NotesRat uterotrophic assay
Described effects
Effect on estrogen: Increased uterus weight
Effect on estrogen: 600-800 mg/kg: premature vaginal opening
Literature references
Ashby, J., Tinwell, H.(1998). Uterotrophic activity of bisphenol A in the immature rat.Environ. Health Perspect., 106: 719-720
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.