ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Bisphenol A
Study details
Groupyeast
OrganismYeast strain PCY2
TissuehER
Age
InVivoIn vitro
LabLaboratory
Flow
DurationOvernight
Route
Temperature
ConcentrationEC50 = 3.09 µM
Notes
Described effects
Effect on estrogen: Induction of hER dimerization (101.2% of maximal estradiol response)
Literature references
Sheeler, C.Q., Dudley, M.W., Khan, S.A.(2000). Environmental estrogens induce transcriptionally active estrogen receptor dimers in yeast: activity potentiated by the coactivator RIP140.Environ. Health Perspect., 108: 97-103
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.