ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Bisphenol A
Study details
Groupmammalian
OrganismHuman
TissueMCF-7 cells
Age
InVivoIn vitro
LabLaboratory
Flow
Duration6 days
Route
Temperature
Concentration10 nM - 10 µM
NotesE-screen
Described effects
Effect on estrogen: Induction of proliferation (full agonist)
Effect on estrogen: Relative potency to 17-beta-estradiol: 0.01%
Literature references
Perez, P., Pulgar, R., Olea-Serrano, F., Villalobos, M., Rivas, A., Metzler, M., Pedraza, V., Olea, N.(1998). The estrogenicity of bisphenol A-related diphenylalkanes with various substituents at the central carbon and the hydroxy groups.Environ. Health Perspect., 106: 167-174
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.