ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
home login contact pictures
 
planning background results databases partners users
ED North Database
Bisphenol A
Study details
Groupmammalian
OrganismMouse
TissuePXR
Age
InVivoIn vitro
LabLaboratory
Flow
Duration36 hours
Route
Temperature
Concentration10 pM - 10 µM
NotesCOS-7 cells transfected with PXR expression plasmid
Described effects
suspected no endocrine effect
No induction of PXR-mediated transcription
Literature references
Masuyama, H., Hiramatsu, Y., Kunitomi, M., Kudo, T., MacDonald, P.N.(2000). Endocrine disrupting chemicals, phtalic acid and nonylphenol, activate pregnane X receptor-mediated transcription.Mol. Endocrinol., 14: 421-428
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.