ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Bisphenol A
Study details
Groupmammalian
OrganismWistar rat, male
TissueLiver
Age
InVivoIn vivo
LabLaboratory
Flow
Duration24 hours
RouteIntraperitoneal
Temperature
Concentration0.3 mg/kg
Notes
Described effects
suspected endocrine effect
Increased CYP3A1 mRNA expression
Literature references
Masuyama, H., Hiramatsu, Y., Kunitomi, M., Kudo, T., MacDonald, P.N.(2000). Endocrine disrupting chemicals, phtalic acid and nonylphenol, activate pregnane X receptor-mediated transcription.Mol. Endocrinol., 14: 421-428
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.