ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Bisphenol A
Study details
Groupmammalian
OrganismWistar rat, male
TissueLiver
Age7 weeks
InVivoIn vivo
LabLaboratory
Flow
Duration4 days
RouteIntraperitoneal
Temperature22-26°C
Concentration20-40 mg/kg/day
NotesDose range: 10-40 mg/kg
Described effects
suspected endocrine effect
Altered expression and activities of male-specific cytochrome P450 isoforms
Literature references
Hanioka, N., Jinno, H., Nishimura, T., Ando, M.(1998). Suppression of male-specific cytochrome P450 isoforms by bisphenol A in rat liver.Arch. Toxicol., 72: 387-394
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.