ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
home login contact pictures
 
planning background results databases partners users
ED North Database
Bisphenol A
Study details
Groupmammalian
OrganismCrl:CD BR Sprague-Dawley rat
Tissue
AgePre- and postnatal
InVivoIn vivo
LabLaboratory
Flow
DurationGestation day 11 to postnatal day 20
RouteMaternal transfer (in utero and lactation)
Temperature22-25°C
Concentration3.2-320 mg/kg/day
NotesDams were dosed by gavage
Described effects
suspected no endocrine effect
Female offspring: no apparent adverse effects on pubertal development and reproductive functions
suspected no endocrine effect
Male offspring: no significant effects on reproductive organ weights and micromorphology
Literature references
Kwon, S., Stedman, D.B., Elswick, B.A., Cattley, R.C., Welsch, F.(2000). Pubertal development and reproductive functions of Crl:CD BR Sprague-Dawley rats exposed to bisphenol A during prenatal and postnatal development.Toxicol. Sci., 55: 399-406
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.