ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Bisphenol A
Study details
Groupamphibian
OrganismXenopus laevis (African clawed frog)
TissueHepatic ER
AgeAdult
InVivoIn vitro
LabLaboratory
Flow
Duration24 hours
Route
Temperature4°C
ConcentrationIC50 = 30.2 µM
Notes
Described effects
Effect on estrogen: Inhibition of [3H]estradiol binding to ER
Literature references
Lutz, I., Kloas, W.(1999). Amphibians as a model to study endocrine disruptors: I. Environmental pollution and estrogen receptor binding.Sci. Total Environ., 225: 49-57
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.