ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Bisphenol A
Study details
Groupamphibian
OrganismXenopus laevis (African clawed frog), male
TissueHepatocytes
AgeAdult
InVivoIn vitro
LabLaboratory
Flow
Duration36 hours
Route
Temperature20°C
Concentration0.1-10 µM
NotesDose range: 0.1 nM - 10 µM
Described effects
Effect on estrogen: Induction of VTG mRNA
Literature references
Kloas, W., Lutz, I., Einspanier, R.(1999). Amphibians as a model to study endocrine disruptors: II. Estrogenic activity of environmental chemicals in vitro and in vivo.Sci. Total Environ., 225: 59-68
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.