ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Bisphenol A
Study details
Groupamphibian
OrganismXenopus laevis (African clawed frog)
Tissue
AgeLarva (2-3 days)
InVivoIn vivo
LabLaboratory
FlowSemi-static
Duration12 weeks
RouteWater
Temperature22-23°C
Concentration100 nM
NotesDose range: 10-100 nM
Described effects
Effect on estrogen: Increased number of female phenotypes
Literature references
Kloas, W., Lutz, I., Einspanier, R.(1999). Amphibians as a model to study endocrine disruptors: II. Estrogenic activity of environmental chemicals in vitro and in vivo.Sci. Total Environ., 225: 59-68
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.