ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Bisphenol A
Study details
Groupmammalian
OrganismHuman
TissueMCF-7 cells
Age
InVivoIn vitro
LabLaboratory
Flow
Duration5 days
Route
Temperature37°C
Concentration0.542-3.01 µg/l
NotesE-screen; concentrations in influent of municipal sewage plant; chemicals measured: 4-tert-octylphenol, 4-nonylphenol, bisphenol A, 4-chloro-3-methylphenol and butylhydroxyanisole
Described effects
Effect on estrogen: Dose-dependent induction of cell proliferation (RPE > 70%)
Effect on estrogen: EEQ: 58-70 ng/l
Effect on estrogen: Quantified phenolic compounds: 0.72-0.83% of total estrogenic activity
Literature references
Körner, W., Bolz, U., Süsmuth, W., Hiller, G., Schuller, W., Hanf, V., Hagenmaier, H.(2000). Input/output balance of estrogenic active compounds in a major municipal sewage plant in Germany.Chemosphere, 40: 1131-1142
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.