ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Bisphenol A
Study details
Groupfish
OrganismOncorhynchus mykiss (Rainbow trout)
Tissue
AgeJuvenile
InVivoIn vivo
LabLaboratory
Flow
Duration9 days
RouteIntraperitoneal
Temperature
Concentration50 mg/kg
NotesSingle dose at day 0
Described effects
Effect on estrogen: Approximately 300-fold increases in plasma VTG levels
suspected no endocrine effect
Increased HSI
Literature references
Christiansen, L.B., Pedersen, K.L., Korsgaard, B., Bjerregaard, P.(1998). Estrogenicity of xenobiotics in rainbow trout (Oncorhynchus mykiss) using in vivo synthesis of vitellogenin as a biomarker.Mar. Environ. Res., 46: 137-140
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.