ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Dicofol (Kelthane)
Study details
Groupmammalian
OrganismRat
Tissue
Age
InVivoIn vivo
LabLaboratory
Flow
Duration2 generations
Route
Temperature
ConcentrationLOEL = 2.5 mg/kg body weight/day
Notes
Described effects
suspected endocrine effect
Ovarian stromal cell hyperplasia
suspected endocrine effect
Hepatocellular changes
Literature references
Toppari,J., Larsen, J.C., Christiansen, P., Giwercman, A., Grandjean, P., Guillette, L.J., Jr., Jégou, B., Jensen, T.K., et al.(1995). Male reproductive health and environmental chemicals with estrogenic effects.Miljoprojekt nr. 290, Report of the Ministry of Environmental and Energy, Danish Environmental Protection Agency, Kobenhavn, Denmark, 166p
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.