ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Lindane (gamma-Hexachlorocyclohexane)
Study details
Groupmammalian
OrganismRat, male
Tissue
AgeMature
InVivoIn vivo
LabLaboratory
Flow
Duration45 days
RouteIntraperitoneal
Temperature
Concentration8 mg/kg/day
Notes
Described effects
suspected endocrine effect
Reduced testicular weight
suspected endocrine effect
Degeneration of Leydig cells
suspected endocrine effect
Decreased serum testosterone concentrations
Literature references
Chowdhury, A.R., Gautum, A.K.(1994). Steroidgenic impairment after lindane treatment in male rats.Journal of UOEH, 16: 145-152
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.