ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Lindane (gamma-Hexachlorocyclohexane)
Study details
Groupmammalian
OrganismAlbino rat, male
Tissue
AgeAdult
InVivoIn vivo
LabLaboratory
Flow
Duration10 days
RouteIntraperitoneal
Temperature
Concentration4-8 mg/kg/day
Notes
Described effects
suspected endocrine effect
Decreased testis weight
suspected endocrine effect
Cell abnormalities in testis
Effect on anti-androgen: Inhibition of spermatogenesis
Literature references
Chowdhury, A. R., Venkatakrishna-Bhatt, H., Gautam, A.K.(1987). Testicular Changes of Rats Under Lindane Treatment.Bull. Environ. Contam. Toxicol., 38: 154- 156
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.