ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Lindane (gamma-Hexachlorocyclohexane)
Study details
Groupmammalian
OrganismWistar rat, male offspring
Tissue
Age7 months
InVivoIn vivo
LabLaboratory
Flow
Duration
RouteMaternal transfer
Temperature
Concentration30 mg/kg
NotesSingle dose to mother on day 15 of pregnancy
Described effects
suspected endocrine effect
Reduced serum testosterone concentrations
suspected endocrine effect
Reduced sexual behaviour
suspected no endocrine effect
No effects on number of sperm and spermatids and testis weight
Literature references
Dalsenter, P.R., Faqi, A.S., Chahoud, I.(1997). Serum Testosterone and Sexual behaviour in Rats after Prenatal Exposure to Lindane.Bull. Environ. Contam. Toxicol., 59: 360-366
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.