ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Lindane (gamma-Hexachlorocyclohexane)
Study details
Groupmammalian
OrganismSwiss mouse, female
Tissue
AgeAdult, pregnant
InVivoIn vivo
LabLaboratory
Flow
Duration4-6 days
RouteOral
Temperature
Concentration3.6-10.4 mg/kg/day
NotesDosing during various stages of pregnancy
Described effects
suspected endocrine effect
Failure in implantation and fetotoxicity
Literature references
Sircar, S., Lahiri, P.(1989). Lindane (gamma-HCH) causes reproductive failure and fetotoxicity in mice.Toxicology, 59: 171-177
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.