ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Lindane (gamma-Hexachlorocyclohexane)
Study details
Groupmammalian
OrganismMustela vison (Mink)
Tissue
Age
InVivoIn vivo
LabLaboratory
Flow
DurationMulti-generation study
RouteFood
Temperature
Concentration1 mg/kg/day
NotesExposure from conception to maturity
Described effects
suspected endocrine effect
Decreased litter size
suspected endocrine effect
F3 males: decreased testis size
Effect on thyroid hormone: F2 males: decreased serum T4 levels
suspected no endocrine effect
No effect on serum cortisol, testosterone and estradiol levels
Literature references
Beard, A.P., Rawlings, N.C.(1998). Reproductive effects in mink (Mustela vison) exposed to the pesticides lindane, carbofuran and pentachlorophenol in a multigeneration study.J. Reprod. Fertil., 113 95-104
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.