ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Lindane (gamma-Hexachlorocyclohexane)
Study details
Groupmammalian
OrganismWestern white face ewe
Tissue
Age1-3 years
InVivoIn vivo
LabLaboratory
Flow
Duration
RouteFood
Temperature
Concentration1 mg/kg body weight/day
NotesDosing 5 weeks prior to mating and throughout pregnancy lactation
Described effects
suspected endocrine effect
Reduced pregnancy rate
suspected endocrine effect
Increased thyroid follicle size
Literature references
Beard, A.P., Bartlewski, P.M., Rawlings, N.C.(1999). Endocrine and reproductive function in ewes exposed to the organochlorine pesticides lindane or pentachlorophenol.J. Toxicol. Env. Health, Part A, 56: 23-46
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.