ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Alachlor
Study details
Groupmammalian
OrganismHuman
Tissue
Age
InVivoIn vitro
LabLaboratory
Flow
Duration1 hour
Route
Temperature
ConcentrationNOEL = 1 µM
Notes
Described effects
suspected no endocrine effect
No interaction with ER
Effect on anti-estrogen: Mixture of dieldrin and alachlor reduced specific binding of estradiol to ER
Literature references
Arnold, S.F., Vonier, P.M., Collins, B.M., Klotz, D.M., Guillette, L.J., Jr., McLachlan, J.A.(1997). In vitro synergistic interaction of alligator and human estrogen receptors with combinations of environmental chemicals.Environ. Health Perspect., 105 (3): 615-618
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.