ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Hexachlorobenzene
Study details
Groupmammalian
OrganismSyrian hamster, male
Tissue
Age
InVivoIn vivo
LabLaboratory
Flow
Duration6-28 weeks
RouteFood
Temperature
Concentration100-500 ppm
Notes
Described effects
Effect on thyroid hormone: Decreased serum T3 levels, no effect on serum T4
suspected endocrine effect
Increased thyroid size
Literature references
Smith, A.G., Dinsdale, D., Cabral, J.R., Wright, A.L.(1987). Goitre and wasting induced in hamsters by hexachlorobenzene.Arch. Toxicol., 60: 343-349
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.