ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Hexachlorobenzene
Study details
Groupmammalian
OrganismSprague-Dawley rat
Tissue
Age
InVivoIn vivo
LabLaboratory
Flow
Duration2-generation study
RouteFood
Temperature
Concentration40 ppm
NotesConcentration range: 0.32-40 ppm
Described effects
suspected no endocrine effect
No effect on fertility
suspected endocrine effect
F1: increased incidence of parathyroid adenomas
Literature references
Arnold, D.L., Moodie, C.A., Charbonneau, S.M., Grice, H.C., McGruire, P.F., Bryce, F.R., Collins, B.T., Zawidzka, Z.Z. et al.(1985). Long-term toxicity of hexachlorobenzene in the rat and the effect of dietary vitamin A.Food Chem.Toxicicol., 23: 779-793
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.