ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Nonylphenol
Study details
Groupmammalian
OrganismHuman
TissueMCF-7 cells
Age
InVivoIn vitro
LabLaboratory
Flow
Duration12 hours
Route
Temperature
Concentration1-10 µM
NotesConcentration range: 0.1- 10 µM
Described effects
Effect on estrogen: Induction of hER-mediated transcription
Literature references
Lascombe, I., Beffa, D., Rüegg, U., Tarradellas, J., Wahli, W.(2000). Estrogenic activity assessment of environmental chemicals using in vitro assays: identification of two new estrogenic compounds.Environ. Health Perspect., 108: 621-629
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.