ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Nonylphenol
Study details
Groupmammalian
OrganismMouse
TissueHeLa cells
Age
InVivoIn vitro
LabLaboratory
Flow
Duration16 hours
Route
Temperature
Concentration0.1 nM - 10 µM
NotesHeLa cells transfected with ERalpha and ERbeta, respectively
Described effects
Effect on estrogen: Dose-dependent induction of ERalpha- and ERbeta-mediated gene expression
Literature references
Balaguer, P., François, F., Comunale, F., Fenet, H., Boussioux, A.M., Pons, M., Nicolas, J.C., Casellas, C.(1999). Reporter cell lines to study the estrogenic effects of xenoestrogens.Sci. Total Environ., 233: 47-56
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.