ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Tributyltin (Tributylstannane)
Study details
Groupmollusc
OrganismRuditapes decussata (Clam)
Tissue
AgePost-spawning
InVivoIn vivo
LabLaboratory
Flow
Duration7 days
RouteWater
Temperature
Concentration0.1-2.27 µg/l
NotesConcentrations as Sn
Described effects
suspected endocrine effect
Increased testosterone levels
suspected endocrine effect
Decreased aromatization of testosterone to estrone and estradiol
Literature references
Morcillo, Y., Ronis, M.J.J., Solé, M., Porte, C.(1998). Effects of tributyltin on the cytochrome P450 monooxygenase system and sex steroid metabolism in the clam Ruditapes decussata.Mar. Environ. Res., 46: 583-586
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.