ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Tributyltin (Tributylstannane)
Study details
Groupmollusc
OrganismRuditapes decussata (Clam)
TissueDigestive gland microsomes
Age
InVivoIn vitro
LabLaboratory
Flow
Duration20 min
Route
Temperature
Concentration0.1-1 mM
Notes
Described effects
suspected endocrine effect
Reduction in the total metabolism of testosterone
suspected endocrine effect
Altered testosterone metabolite profile
Literature references
Morcillo, Y., Ronis, M.J.J., Solé, M., Porte, C.(1998). Effects of tributyltin on the cytochrome P450 monooxygenase system and sex steroid metabolism in the clam Ruditapes decussata.Mar. Environ. Res., 46: 583-586
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.